WBC-Platelet Recovery Trajectories
Visualizing Inflammatory Recovery Dynamics
Explore how white blood cell (WBC) and platelet (PLT) counts co-evolve during inflammatory recovery. Based on our Nature Communications 2022 paper, this tool visualizes recovery trajectories in 2D WBC-PLT phase-plane.
Tip: Enter paired WBC and platelet values (same number of values in each). Minimum 3 time points required.
📈 Time Series View
🔄 2D Trajectory in WBC-PLT Space
📖 About This Method
What it does: This tool visualizes the co-regulatory dynamics between white blood cells (WBC)
and platelets (PLT) during inflammatory recovery. These values are plotted against an example 'ideal' recovery trajectory,
where PLT count increases linearly, and WBC count decays exponentially. We showed that this model accurately captures
healthy recovery dynamics following acute inflammatory events (trauma, ischemia, infection). Significant deviations from
this trajectory were associated with drastically increased mortality, across diverse clinical settings.
Note: The reference trajectory is illustrative only. Exact, context-specific reference trajectories can be found in the associated
paper.
Learn more: Our Research | Nature Communications paper | Publications